The change of multifocal visual evoked potential (mfVEP) in unilateral anisometropic amblyopia before and after occlusion treatment.

1. Moohwan Chang
2. Sungeun Kyung
3. Jihoon Jeon

Department of ophthalmology, Dankook university Hospital, Cheonan, South Korea

Purpose : To investigate the change of multifocal visual evoked potential (mfVEP) in unilateral amblyopia due to anisometropia before and after amblyopia treatment.

Method : We record mfVEP in both eyes in 7 anisometropic amblyopia who have been treated for amblyopia at least 6 months. The changes in latency and amplitude were compared between before and after occlusion.

Results: There was increased amplitude in amblyopic eye after amblyopia treatment. The latency after treatment in amblyopic and fellow eye was not different from before treatment. There was no significant difference in latency or amplitude before and after amblyopia treatment. There was a significant difference in the amplitude of ring 1 compared with other ring area in amblyopic and fellow eyes after amblyopia treatment(P<0.05).

Conclusion: The responses in the central region of the visual field (rings 1), which represents the foveal area, were statistically significant increase of amplitude in the amblyopic and fellow eye after treatment. These results suggest that mfVEP may be used as an objective method for monitoring of anisometropic amblyopia after occlusion treatment.