Analysis of Retinal Nerve Fiber Layer Thickness and Optic Disc Morphology using Spectral Domain Optical Coherence Tomography in Paediatric eyes

1. Usha Kaul Raina
2. Gauri Bhushan
3. Basudeb Ghosh
4. Meenakshi Thakar
5. Neha Goel
6. Bhanu Pratap Singh Pangtey

Guru Nanak Eye Center, Delhi, India

Purpose: To collect a normative database of Retinal Nerve Fiber Layer thickness and Optic Nerve Head Topography in the healthy eyes of children aged 5-15 years using RTVue Spectral domain Optical coherence Tomography (SD-OCT).

Methods: Scans were obtained for 100 healthy Indian children, total 200 eyes. Each child had both eyes OCT measurement using the RNFL thickness protocol and ONH protocol of RTVue, RT100, Optovue, Inc. In addition each child had a dilated eye examination, an axial length measurement and retinoscopy done.

Results: All the children tolerated the tests well. The average RNFL thickness was recorded as 105.61µm( SD 11.0)(range 65-133). Average thickness was maximum in Superior Quadrant 136.69µm(range 79-196) and minimum in Temporal Quadrant 76.47µm(range 49-116). Cup Disc Ratio on an average was 0.296 (range 0.1- 0.9).
In 14 children Cup Disc Ratio was unrecordable. Axial length showed negative correlation with RNFL thickness.

Conclusions: Studies have been done using Time domain OCT in children but there is no study generating data using spectral domain OCT for children in the Indian subcontinent.This data will be useful as a reference for screening of glaucoma in children and in assessing other childhood diseases affecting the Retinal Nerve Fiber Layer. group.