The Effect of Subconjunctival Bevacizumab Injection on Corneal Neovascularization

1. Maula Rifada
2. Susi Heryati
3. Budiman

Department of Ophthalmology Padjadjaran University – Cicendo Eye Hospital, Bandung, Indonesia

Purpose: To evaluate the short term effect of subconjunctival bevacizumab on corneal neovascularization.

Methods: a case report of a 31 years old man with corneal vascularization following phakic IOL reposition.

Results: A 31 years old man complained of blurred vision in the right eye with history of phakic IOL reposition 1 year ago due to decenteration. Best corrected visual acuity in the right eye was 0.1. Slit-lamp examination revealed localized corneal edema with transudation and superficial and deep neovascularization at the temporal corneolimbal region. The eye was treated with subconjuctival 2.5 mg Bevacizumab unjection, topical prednisolone acetate, artificial tears, and methyl prednisolone oral (1 mg/kgBW). Two weeks of Bevacizumab injection, the superficial and deep corneal neovascularization was markedly reduced.

Conclusion: Subconjunctival Bevacizumab injection was effective in reducing corneal neovascularization in short term evaluation but long term follow up are required.