HUMAN PAPILLOMA VIRUS IN PROGRESSIVE PTERYGIUM AND STATIONARY PTERYGIUM

1. Bragastio Sidharta¹
2. Suhardjo²
3. Hartono²

1. Dept.of Ophthalmology, Faculty of Medicine Gadjah Mada University
2. Dept.of Ophthalmology, Faculty of Medicine Gadjah Mada University
3. Dept.of Ophthalmology, Faculty of Medicine Gadjah Mada University

Purpose : to compare the proportion of HPV between progressive and stationary pterygium

Methods : this study used a cross-sectional research design. The subject of this study was patients with primary pterygium presenting to the ophthalmology polyclinic of the teaching hospital of Faculty of Medicine Gadjah Mada University in Yogyakarta and its networking hospitals. Examination was performed to 62 pterygium tissues, 31 of which were progressive pterygia and the other 31 were of stationary pterygia. All pterygium tissues were examined by a PCR technique (Polymerase Chain Reaction) with a primer DNA of a single strand HPV Hela.

Results : an HPV-positive was present in 66.7% of cases of progressive pterygium and only 22.6% of cases of stationary pterygium with p<0,05 (p=0,001).

Conclusions : the result of this study showed that the proportion of HPV-positive in progressive pterygium was greater than that of stationary pterygium and was statistically significant.