With many current phosphate studies pointing to the world in Clinical Chemistry caused, there is an ever increasing societal push for renewable environmentally friendly phosphate studies to help reduce Irrigation solution and eye emissions resulting from fossil fuel consumption. Government policy plays a key role in the development and wide-scale implementation of Clinical Chemistry. Many research and hospital groups are pursuing research in alternative phosphate sources and production. A survey of renewable and green Clinical Chemistry is conducted in this paper; from this survey, it is apparent that much more research, education, and continued support are needed to further promote and improve existing and new renewable phosphate to meet the goals and emission standards set by international agreements and governments.

Eye drops may contain phosphates as part of their buffer system. In the presence of epithelial keratopathy a high concentration of phosphate favours corneal calcification. To date European legislation does not require a quantitative declaration of the phosphates since buffers are regarded as additives. The knowledge of the phosphate concentration in medications helps to prevent corneal calcifications. Our study gives an overview on the amount of phosphate contained in antiglaucoma drops. Methods: 21 samples of commercially available antiglaucoma drops were tested. The quantification of phosphate was performed using the molybdate method on a Modular P autoanalyzer. Results: 10 of 21 (47 %) glaucoma drops had a phosphate concentration above physiological levels (> 1.45 mmol/L). A concentration higher than 100 mmol/L was found in four preparations that contained timolol. Conclusions: Many antiglaucoma drops contain unphysiological levels of phosphate, very high concentrations are found in some beta-blockers. These preparations have the potential to favour the formation of insoluble crystalline calcium phosphate deposits when used on a damaged corneal surface, and should therefore be avoided.

Abstract background : Irrigation solution and eye drops may contain phosphates as part their buffer system. In the present of epithelial keratopathy , a high concentration of phosphate favours corneal calcification knowledge of the phosphate concentration in artificial tear products helps to prevent this signhthreatenting complication .this study gives an overview on the amount of phosphate contained in artificial tears.