Mid-term Results Of Filtering Surgery In Corticosteroid-induced Glaucoma Patients

Jing Fu

Purpose: To analyze the mid-term effect of filtering surgery in patients with
corticosteroid-induced glaucoma (CIG).

Methods: This case-series study consisted of 22 eyes of 15 corticosteroid-induced glaucoma patients who received trabeculectomy or non-penetrating trabecular surgery (NPTS) from March 2005 to March 2008. Both preoperative and postoperative intraocular pressure (IOP), cup –disk ratio, Humphrey visual fields, number of glaucoma medications were recorded. Characteristics of postoperative blebs were analyzed with UBM and slit-lamp. Bleb grading and UBM were performed on all glaucoma surgery eyes on the ending time point of the study.

Results: 16 eyes were performed trabeculectomy, 6 eyes were performed NTPS. Mean IOP before and after trabeculectomy or NPTS were 29.82±11.87 and 1.61±3.58 mmHg (p<0.01), respectively. The mean vertical cup-disk ratio (VCDR) was 0.54 before surgery compared with a VCDR of 0.55 after surgery. No significant changes were found in visual fields before and after surgery (P=0.06). According to the outcome of final IOP, success rate was 100%. Based on slit-lamp and UBM evaluation of the bleb, 90.9% of blebs were functional filtering bleb and 9.1% were non-functional filtering blebs.

Conclusions: The mid-term result of filtering surgery in CIG patients indicates a successful outcome of IOP control, stable VCDR and visual fields without antiglaucoma medication.