MRI-Determined Subretinal Fluid Volume In A Patient With Harada Disease

1. Satoshi Okimoto
2. Yoshiaki Kiuchi
3. Takashi Sone

Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan

Purpose : Magnetic resonance imaging (MRI) performed with microscopy surface coils can help improve spatial resolution, and provide detailed morphological information. Using this method, we could successfully measure the volume of the subretinal fluid in a patient with non-rhegmatogenous retinal detachment and follow its changes during treatment.

Methods : A 56-year-old male who had lost his central visual field at age 30 years due to glaucoma developed sensorineural hearing loss in both ears, and severe headaches developed. He then developed uveitis in both eyes. After treating the anterior uveitis by topical steroids, cataract surgery was performed on both eyes. He was found to have non-rhegmatogenous retinal detachment with movement of the subretinal fluid with changes in posture. We diagnosed uveitis was due to Harada disease and treated him with steroid pulse therapy. We could not accurately evaluate the improvement of the retinal detachment by ophthalmoscopy and B-scan ultrasonography. We measured the volume of the subretinal fluid in the MRI four times during the treatment period. The volume of the subretinal fluid decreased gradually. The reproducibility of the measurements of the volume by MRI was excellent with a coefficient of variation of 2.8% for the volume of the whole eyeball, and 7.9% for the volume of the anterior chamber.

Conclusion : The adaptation of MRI performed with a surface coil can not only obtain the funds image in eyes with clouded media but also evaluate the volume of determined space.