Histiocytoses –3 case series

Golam Haider¹, Mukti Rani Mitra², Bhowmik Roy Swapan Kumar³, Nizamuddin Faruqe⁴, Syed Shaheen Iqbal⁵, Soheli Nasreen⁶.

National Institute of Ophthalmology and Hospital Agargaon, Dhaka-1207, Bangladesh

¹Associate Professor (Oculoplasty), NIO,H
²Registrar, NIO,H
³Assistant Professor(Oculoplasty), NIO,H
⁴Associate Professor, NIO,H
⁵Assistant registrar, NIO,H
⁶Assistant registrar, NIO,H

Purpose: To report three cases of Histiocytoses.

Method: Prospective interventional case series.

Result: Three patients aged 35(female, Gajipur), 42(male, Keraniganj), and 3 years (female, Dhamrai) presented in the oculoplasty clinic of National Institute of Ophthalmology and Hospital and Harun Eye Foundation Hospital, Dhaka, Bangladesh this year. The two adult patients presented with a bilateral symmetrical, painless, yellowish-white, firm nodular mass fixed with the underlying structure and with the skin involving the whole lower lids and isolated mass in the superomedial region of both upper lid. Visions were unaffected. The three years old child had a soft, painless, diffuse mass in the lateral part of the left upper and lower eyelids extending to the forehead and cheek. CT scan showed heterogenous irregular mass with bone erosion. Incision biopsy was done all cases. Debulking was done in adult male and female. Histopathologic confirmation was done for Langerhans Cell Histiocytosis in child and non-Langerhans Cell Histiocytosis in adult male and female.

Conclusion: Histiocytoses are a rare disease. Management is difficult. It may be benign, locally aggressive or malignant. So early diagnosis and prompt treatment is essential.