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Intravitreal bevacizumab for choroidal neovasucularization from tilted disc syndrome 1. Tomoko Asai, M.D.¹ ¹Department of Ophthalmology E7, Osaka University Graduate School of Medicine, Osaka, Japan Purpose: Tilted disc syndrome (TDS) sometimes develops choroidal neovascularization (CNV). We report 3 cases of CNV from TDS treated with intravitreal bevacizumab (IVB). Cases presentation: Case 1: A 67-year-old lady was referred with a decreased vision OS. The best-corrected visual acuity (BCVA) was 20/400. Fundus observation revealed CNV from TDS. Spherical equivalent refractive error (SERE) was -8.25D and axial length 27.75mm. Eye was treated with IVB (1mg), and BCVA improved to 20/150 6 months after. Although optical coherence tomography (OCT) disclosed resolution of subretinal fluid (SRF), fluorescein angiogram still showed minimum persistent leakage from CNV. Case 2: A 79-year-old lady came with a visual loss OD for last one month. CNV associated with TDS was presented. BCVA was 20/100. SERE was -1.5D with pseudophakic eye, and axial length 24.12mm. We treated with IVB however BCVA unchanged. One year after, fluorescein leakage was diminished, however there was still SRF around CNV in OCT examination. Case 3: A 27-year-old male was referred due to metamorphopsia OS. The BCVA was 20/50. The SERE was -14.75D and axial length 28.78mm. IVB was performed for CNV from TDS and it was stabilized 6 months after with an unchanged vision of 20/50. New CNV appeared at the superior edge of the original CNV 1 year after, resulting in decreased vision to 20/120. Conclusion: Given the favorable results of IVB for myopic or idiopathic CNV, IVB for TDS-related CNV does not seem to meet the patients' satisfaction. |
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