"Assesment of the trabeculectomy with 5- Fluorouracil in the treatment of post- traumatic glaucoma".

Yen Thu Thi Nguyen

National Institute of Ophthalmology, Hanoi, Vietnam

Purpose: Eye injury commonly results in severe visual loss results from both the inital effect of the injury and from delayed complication. One of complications was post- traumatic glaucoma. Aim of this study is to describe clinical characteristic and assess the results of trabeculectomy with intraoperative application of 5 Fluorouracil .

Methods: A prospective analysis was undertaken of 32 drainage procedures perfomed on 2 years- period at Trauma Department in National Institute of Ophthalmology, Hanoi -Vietnam. 5- Fluorouracil was applied betwen the sclera and conjictiva for 5 minutes at the time of surgery. The intra \ocular pressure ( IOP) and visual acuity were mesured postoperatively and folow –up at least 6 months.

Results: Of the 32 patients, 29 were men ( 90,6%). The age from 16 to 45 was 71,9%. Trauma due to labor condition : 40,6%. Blunt trauma: 84,4%. Time of posttraumatic glaucoma appears in the first month after trauma: 59,4%. Combined damages were: Subluxated lens: 62,5%( 20/32 eyes), vitreous in anterior chamber: 25%, vitreous hemorrhage: 37,5%, hyphema: 18,8%, iris dialysis: 9,4%. Post- traumatic angle recession: 8/16 eyes ( only 16 eyes were perfomed gonioscopy). Initial visual acuity was 5/200 or worse: 62,5%. After the operation the IOP was successfully controlled at time of folow up: one month : 90,6%, 3 month: 93,8%, six month in 93,8%. The final visual acuity was 0,02 and better in 62,5%.

Conclusion: In medically uncontrolled post- traumatic glaucoma, trabeculectomy with antimetabolite therapy ( 5FU) is effective surgical prrocedure to reduce intraocular pressure in post- traumatic glaucoma.