Laser Peripheral Iridoplasty in the Management of Angle-closure Glaucoma£ºA 39 months Follow-up Study

Wei Zhou

Purpose To explore the long-term outcome of laser peripheral iridoplasty (LPI) in the management of angle-closure glaucoma.

Methods A total of 75 LPI procedures were performed on the consecutive 75 eyes with early angle-closure glaucoma and their iris root closed to trabecular meshwork showed by ultrasound biomicroscopy (UBM). A double-frequency Nd:YAG was used in LPI and laser parameter was 300~500 mW power, 0.3 second duration, 500 μm spot size, 24~30 burns over 360 degree. Patients were termly assessed for postoperative visual acuity，intraocular pressure，medication score，gonioscopy，and UBM.

Results The mean follow-up was 26±6.2 months (range 19~39 months). Comparing with preoperation，postoperative average IOP decreased significantly （F=45.454，P=0.000），medication score reduced significantly （F=48.715，P=0.000），AOD500 increased significantly （F=46.567，P=0.000）. Angle open degree returned to the baseline was 12%，26%，55% , respectively at 1、2、3 year postoperatively（X2 =11.772，P=0.003）.

Conclusion With elapse of time after LPI, angle open degree of angle-closure glaucoma returned to baseline gradually，and effect of depressing IOP weakened.