Fig. 23. Leber's optic atrophy. A. Family B pedigree. Three young sons with useful vision in one of six eyes. Mother, age 28 years, suffered acute bilateral loss of vision at age 14 years, with slowly progressive recovery over 6 years. Maternal uncle, age 74, suffered acute bilateral loss of vision at age 18. Note oblique transmission in the female line. Arrows indicate persons examined. B. Typical dense central field defects.