Fig. 1. Vitreous collagen fibril structure. This schematic diagram of the structure of the major heterotypic collagen fibrils of vitreous is largely speculative but based on the current knowledge of the structure and biophysical attributes of the constituent molecules, particularly in how they would assemble to form fibrils. (From Bishop P: The biochemical structure of mammalian vitreous. Eye 10:64, 1996.)