Fig. 7. Fibrous structure of human vitreous during old age. The vitreous body of an 88-year-old woman has undergone substantial degeneration in the fibrous structure. Fibers are thickened and tortuous. The entire vitreous body appears to have undergone dissolution with empty spaces adjacent to the thickened fibers. (Sebag J: Age-related changes in human vitreous structure. Graefes Arch Clin Exp Ophthalmol 22:89, 1987. Specimens courtesy of the New England Eye Bank, Boston, MA.)