Fig. 8. Human vitreous lacunae in old age. The central vitreous has thickened, tortuous fibers. The peripheral vitreous has pockets devoid of any structure. These contain liquid vitreous and correspond to lacunae as seen clinically on biomicroscopy. (Sebag J, Balazs EA: Human vitreous fibres and vitreoretinal disease. Trans Ophthalmol Soc UK 104:123, 1985.)