Fig. 9. Iris atrophy, presumably due to iris ischemia, commonly occurs in sever and prolonged acute angle-closure glaucoma. In this eye, gray, thin, depigmented areas of atrophy of the iris, most marked at the arrows, are present around the pupillary margin clockwise from 8 o'clock to 3:30. Iris atrophy from high intraocular pressure in angle-closure glaucoma usually involves irregular radial sectors of the iris and is most marked near the pupil. In these sectors, the pupil is usually permanently fixed and dilated as a result of the atrophic process.