Fig. 4. Cystinosis. Top, Transmission electron micrograph showing a stromal keratocyte containing a number of needle-shaped crystalline profiles limited by unit membranes. (× 19,000.) Bottom, Electron micrograph of conjunctival fibrocyte revealing crystalline profiles of sparse granular material within membrane-limited lysosomes. (× 30,000.) (Courtesy of Dr. Kenneth Kenyon)