Fig. 21 Fundus (A) and fluorescein angiogram (B) of right eye, showing macular choriocapillaris and retinal atrophy in a 63-year-old male patient with the Arg172Trp mutation of the peripherin/RDS gene. (From Wells J, Wroblewski J, Keen J, et al: Mutations in the human retinal degeneration slow (RDS) gene can cause either retinitis pigmentosa or macular dystrophy. Nat Genet 3:213–218, 1993)