Fig. 5. A. Fundus photograph and B. fluorescein angiogram, demonstrating diffuse vaso-occlusive disease in a patient with systemic lupus erythematosus. Fluorescein angiogram shows extensive nonperfusion of the retina. (Jabs DA, Fine SL, Hochberg MC, et al: Severe retinal vaso-occlusive disease in systemic lupus erythematosus. Arch Ophthalmol 1104:558, 1986. Copyrighted 1986, American Medical Association. Reprinted with permission.)