Fig. 13 Congenital corneal opacity caused by deposition of glycosaminoglycan in Bowman's layer. A. Infant manifests diffuse, dense, gray corneal clouding. Clouding is most extreme centrally but does extend across the entire cornea. B. Dense accumulation of glycosaminoglycans in Bowman's layer produced this corneal opacity. The epithelium and stroma appear normal (colloidal iron, ×60).