Fig. 14. Hand of child with Apert's syndrome showing proximal syndactyly of digits 2 and 3, 4 and 5 and near-total fusion of digits 3 and 4. (Fries PD, Katowitz JA: Congenital craniofacial anomalies of ophthalmic importance. Surv Ophthalmol 35:87, 1990, with permission from Elsevier Science.)