Fig. 7. Schematic representation of the neural innervation of the conjunctiva. Conjunctival goblet cells are surrounded by parasympathetic and sympathetic nerves, whereas sensory nerves innervate only the stratified squamous cells. The cornea is innervated with sensory nerves, which can activate a neural reflex to stimulate conjunctival goblet cell secretion via parasympathetic nerves releasing Ach and VIP. (Modified from Kessler TL, Mercer HJ, Zieske JD, et al: Stimulation of goblet cell mucous secretion by activation of nerves in rat conjunctiva. Curr Eye Res 14:985–992, 1995.)