Fig. 36. Line graph comparing the human scleral mean permeability (± SD) with the molecular weights (MW) for each of the following 14C compounds tested: 5-fluorouracil, sucrose, inulin, and three dextran polymers (MW = 130, 342, 5,000, 10,000, 40,000, 70,000, respectively). At least five individual perfusions were performed for each data point (n ≥ 5). For the MW of each of the dextran polymers, K = 1,000. This line establishes a baseline human scleral permeability to hydrophilic compounds of varying MW. |