Fig. 3. Time course of mediator release from human basophils (B), MCTC mast cells (TC), and MCT mast cells (T). Granule mediators are preformed; lipid mediators are newly generated; cytokines can be both preformed and newly generated. (After Medical Knowledge Self-Assessment Program [MKSAP]: Allergy and Immunology, p 23. 2nd ed. Philadelphia: American College of Physicians, 1997.)