Fig. 5. Organization of the enterovirus genome. The boxes represent the coding region of the single-strand genomic RNA of enterovirus. A small hydrophobic protein is covalently linked to the terminal uracil of the 5-NTR and called virus protein genome linked (VPg). Region P1 codes for the capsid proteins VP4, VP2, VP1, and VP3. Regions P2 and P3 code for functional proteins.