Fig. 16. Rubella. A. Same eye before (left) and after (right) maximal dilatation with mydriatics. A dense nuclear cataract can be seen in the minimally dilated pupil. Iris is leathery and difficult to dilate (SEI 73–631). (Courtesy of Dr. HG Scheie) B. Iris is atrophic, is infiltrated with plasma cells and lymphocytes (chronic nongranulomatous iritis), and shows a loss of the dilator muscle (H&E, × 130 [SEI 79-36]). (Yanoff M, Schaffer DB, Scheie HG: Rubella ocular syndrome: Clinical significance of viral and pathologic studies. Trans Am Acad Ophthalmol Otolaryngol 72:896, 1968)