Fig. 42. Cornea guttata (Fuchs' combined dystrophy). A. Clinical appearance of an advanced case. B. Epithelium is edematous and contains abnormal basement membranes. Note the formation of bullae. Inset shows high magnification of guttate lesions. C. Advanced changes are present. Note the epithelial edema and thick pannus. BM, Bowman's membrane. (Courtesy of SEI Photoarchives.)