Fig. 31 Metastatic tumors. The appearance of a patient with bilateral metastatic prostate carcinoma to the orbits and eyelids (A). Frame B shows the histopathology of metastatic cutaneous melanoma (met) to mid-orbit adjacent to the optic nerve (on). Frame C is an axial CT scan from a case of disseminated lung carcinoma to the orbit and brain. The lateral wall of the orbit and the temporoparietal fossa are extensively involved with tumor. Frame D reveals metastatic squamous cell carcinoma within a submandibular lymph node from the same case. Immunohistochemical stain reveals a cluster of atypical squamous cell carcinoma cells, stained with brown cytokeratin (D).