Fig. 22. Coats' disease. Thickened, totally detached retina adheres to the back of the lens and the pars plana. The angle is closed by anterior displacement of the lens and iris. The amber gelatinous subretinal exudate contains sparkling cholesterol crystals and clumps of lipid-laden histiocytes. The glaucomatous eye was enucleated because it was blind and painful and retinoblastoma could not be totally excluded.