内引流小梁切除术治疗独眼晚期青光眼临床分析 雷功祖 雷剑琴 邓传芳 张晓萍 林丹
【摘要】目的:评价用内引流小梁切除术(In Flow Trabeculectomy,IFT)对独眼晚期青光眼(另眼为青光眼绝对期无光感或义眼)治疗的安全性和疗效。方法:采用IFT对31例独眼晚期青光眼患者进行治疗,观察患者术后眼压,视力及并发症情况,术后分别随访4-21(平均11.16 ±5.09)个月。结果:31只眼入院时眼压24-66(平均39.09 ±10.34)mmHg,术前眼压5-37(平均16.4 ±7.36)mmHg。术后1周眼压4-17.7(平均10.12 ±3.49)mmHg。随访期眼压8-21((平均13.88 ±2.94)mmHg。术前、后眼压差异具统计学意义(P<0.01)。术前平均使用3.1种降眼压药物,术后下降至0种,差异具统计学意义(P<0.01).所有患者术后无需任何药物治疗,眼压均<21mmHg。患者术后视力较术前增高,差异具统计学意义(P<0.05)。术后3例前房少量积血,1-2天即完全吸收;1例术后4天前房出血,经紧急处理视力恢复,眼压稳定;4眼术后瞳孔区可见少量纤维渗出,2-4天自然吸收。术中、后无浅前房、前房消失、脉络膜脱离、脉络膜上腔出血等并发症出现,随访期无低眼压、视网膜脱离、迟发性眼内炎等并发症。结论:IFT是治疗独眼晚期青光眼简单安全有效的手术方法。
关健词:内引流 小梁切除术
Outcome of inflow Trabeculectomy for late stage glaucoma patients of unique eye Lei gong-zu, Lei jian-qin, ※, Deng chuan-fang , lin dan. Aier Ophthalmology, Chang De 415000, China
[Abstract]
Purpose: Evaluate the safty and effect of IFT for late stage glaucoma patients of unique eye.
Method: A retrospective clinical study. 31 late stage glaucoma patients were included in this study and all of them have lost light perception of the other eye because of glaucoma. IFT was the main treatment for the 31 unique eyes. Follow up last 4~21 months (average 11.16±5.09).
Results: IOP before operation was 24~66mmHg (average 39.09±10.34) and at the end of the follow up, IOP was 8~21mmHg (average 13.88 ±2.94)(P<0.01). No anti-glaucoma ()drug has ever been added after operation. Visual acuity has also significantly improved(P<0.05) 4 patients had hyphema 3~4 days after surgery and all recovered after treatment. No serious complication occur during or after operation.
Conclusion: IFT is a safe and effective option for late stage glaucoma patient of unique eye.
独眼晚期青光眼用常规手术治疗方法成功率低,眼压控制不理想。术中、术后各种并发症多而复杂其病情容易继续恶化,视功能严重损害甚至失明。尽管采用抗代谢药物可以提高手术成功率,但是药物对眼球组织的毒性作用、中晚期出现的薄壁滤过泡、滤泡瘘、迟发性眼内炎等均严重损害视功能。房水引流物植入术并发症多而复杂、远期效果不定,且成本高,不易普及应用。经巩膜睫状体光凝术,眼内窥镜下激光睫状体光凝术,均为破坏性手术,远期疗效不定,且成本高昂,目前很难在基层推广应用。
我们自2004年9月至2006年元月应用系统药物治疗,联合内引流小梁切除术治疗31例独眼晚期青光眼患者, 旨在探讨其治疗效果和手术的安全性。
作者单位:415000 湖南常德 爱尔眼科常德医院(雷功祖 邓传芳 张晓萍 林丹);
西安交通大学第一医院眼科(雷剑琴)
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