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| Beyond the ISCEV Standard: extended electrophysiological techniques in the diagnosis of retinal disease--大会发言 |
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| 作者：Graham E… 文章来源：Moorfields Eye Hospital, London, UK 点击数1870 更新时间：2006/7/6 19:49:00 文章录入：chenyouxin 责任编辑：毛进 |
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| In 1989, the International Society for Clinical Electrophysiology of Vision (ISCEV) introduced a Standard for the performing of clinical electroretinography (ERG). This proposed a minimum data set that should be obtained from all patients, and included a rod specific ERG (dim flash, dark adapted eye); a Standard response (mixed rod-cone, bright flash, dark adapted eye); and two measures of cone function, the response to a 30Hz flicker stimulus and a single flash ERG, both obtained in fully photopic conditions using a rod-suppressing background.
The presentation will address the use of ERG in the diagnosis of retinal disease by using illustrative cases. The results of other investigations, such as fundus autofluorescence imaging, will be shown where appropriate. In addition, the limitations of the Standard will be discussed using clinical examples to show how additional recordings or techniques may be needed, and that ERG recording restricted to the basic Standard responses can even result in misdiagnosis. These additional techniques will include ON-/OFF- response recording, S-cone ERG recording, and the use of extended dark adaptation or altered inter-stimulus intervals.
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