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| Clinical application of keratoprosthesis for chemical burnt corneal opacity unsuitablefor keratoplasty |
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| 作者：HUANG Yi… 文章来源：Professor and Vice Director, Ophthalmic Center of Chinese PLA, Department of Ophthalmology, The General Hospital of PLA , Beijing 100853 , P.R.China 点击数1248 更新时间：2007/6/18 14:43:16 文章录入：aya610 责任编辑：毛进 |
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| To evaluate the visual restoration values of keratoprosthesis(Kpros) for complicated corneal opacities caused by severe chemical burn and unsuitable
for penetrating keratoplasty. Methods: Twenty-eight Kpros were implanted in twenty-eight patients with bilateral corneal blindness. Preoperative visual acuity (VA) was light perception or hand movement in all operated eyes. The corneal opacities were caused by severe alkali burn (20 eyes) and sulfate acid injury (8 eyes). The Kpros ( MICOF.) were made by Moscow Eye Microsurgery Complex in Russia. All the eyes had been given up for any keratoplasty surgery by corneal surgeons before the Kpros surgery. The patients were well informed about the Kpros and the risks associated with. All the eyes were carefully evaluated before the surgery and given regular follow up after the surgery. Surgical techniques consisted of two stages,firstly, inserting a supporting titanium frame into the corneal pocket and secondly, implanting an optical part with combination of lensectomy, iridetomy 3 months later. Results: Follow-up time ranged from 3 to 65 months (22.6 months on average). Postoperatively, 21 of 28 eyes (75%) achieved VA ranged from 0.05 to 1.0 without correction. Corrected VA was: 11 eyes (39%) from 0.6 to 1.2; 1 eye (4 %) from 0.3 to 0.5; 5 eyes(18%) from 0.1 to 0.25; 4 eyes(14%) from 0.05 to 0.08; 3 eyes(11%) hand movement；3 eyes(11%) light perception and 1 eye(4%) with VA no light perception. Conclusion Kpros improves vision for corneal opacity patients with complicated conditions resulted from chemical burn such as dense neovascularization and severe ocular surface disorders.
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