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The significance of the multifocal electroretinogram changes in choroidal neovascularization patients
作者:Li Jiang  文章来源:Shenzhen 1st People Hospital  点击数299  更新时间:2011/9/13 11:58:00  文章录入:毛进  责任编辑:毛进
Purpose  Through the measurement of multifocal electroretinogram (mfERG) in the patient eyes with choroidal neovascularization (CNV) evaluate to the lesions of visual function and the effects of medical treatment.
Method  Sixteen eyes affected with CNV, diagnosed by FFA, ICGA and OCT, were tested with VERIS Science 4.0 before and after the medical treatment. The average response densities and latencies of annular retinal regions were analyzed. The 3-dimension plots of mfERG were observed also.
Results  The average response densities and latencies of CNV eyes were abnormal. Follow up of medical treatment 6 months later the average response density of N1 and P1 in first and second ring increased than before treatment (P, 1st ring = 0.012; P, 2nd ring = 0.031). The differences were significance. But the latencies were no significant difference. 
Conclusion  As the objective visual function testing for macula the mfERG has showed the abnormality in CNV eyes and it was improvement after medical treatment. It determinate the mfERG is useful in evaluation of the visual function changes in macular diseases and with the treatment.  
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