目的  比较两种不同设计的非球面人工晶体植入术后患者对比敏感度的改变。
方法  选择连续入院并拟由同一临床经验丰富的医师完成白内障超声乳化联合人工晶体植入手术的患者63例（90眼），随机分为三组，每组30眼。组A患者植入前表面非球面修饰的人工晶体（AMO Tecnis ZA 9003型），组B植入后表面非球面修饰的人工晶体（Alcon IQ SN60WF型），对照组植入单焦球面晶体（AMO AR40e）。术后6个月对三组患者进行不同照明条件下（3 cd/m²，85 cd/m²），四种不同空间频率下（3c/d，6c/d，12c/d，18c/d）的对比敏感度（CS）测定并进行比较。
结果  两组非球面晶体植入的患者术后对比敏感度较球面晶体植入术的患者更好，其中在低空间频率下（3c/d、6c/d）差距明显（p＜0.05）。在眩光条件下，球面晶体植入患者在高空间频率（18c/d）下的对比敏感度下降（p＜0.05），而非球面晶体组患者则耐受良好。
结论  两种非球面人工晶体都能获得良好的视功能，相比传统的球面型人工晶体，新的非球面设计理念可以带来更好的视觉质量。
Purpose  To compare the contrast sensitivity(CS) of different aspheric intraocular lenses implantation.
Methods  90 patients were randomized to receive three IOL types: an aspheric IOL with a modified anterior surface (AMO Tecnis ZA 9003, 30 eyes, Group A), an aspheric IOL with a modified posterior surface (Alcon IQ SN60WF, 30 eyes, Group B) and an IOL with spherical surface (AMO AR40e, 30 eyes as control group). All the operations were finished by one experienced operator. The contrast sensitivity (CS) under mesopic (3cd/m²) and photopic (85cd/m²) condition with 4 different spatial frequencies of 3, 6, 12,18 cycles per degree(c/d) were performed 6 months postoperatively.
Results  The patients of two aspheric intraocular lenses groups have better contrast sensitivity after operation than the patients with spherical lenses. There is a significant difference between the two aspheric groups and the spherical group under the low spatial frequencies of 3, 6 c/d (p<0.05). With a glare source of 85cd/m2, the patients with spherical lenses have a lower contrast sensitivity under the spatial frequency of 18c/d but two aspheric groups.
Conclusions  The two aspheric intraocular lenses are better for the quality of vision for patients compared with the traditional spherical lenses.