目的 观察眼底荧光造影的不良反应及防范处理措施。 
方法对3125例患者中荧光素钠注射液不良反应的发生率及对其处理进行回顾性研究。
结果 3125例患者中,发生不良反应的共234例,占7.48%。其中大部分为轻、中度不良反应,为219例,发生率7.01%，主要表现为恶心、呕吐、头昏、皮疹；重度不良反应为15例，发生率0.48%，主要表现为晕厥、过敏性休克；无死亡病例。不良反应的发生时间绝大多数在造影开始的1min内。
结论 在检查前要严格掌握好适应症及禁忌症，尽管会发生一些不良反应，眼底血管荧光造影术仍然是一种相对安全的眼底病检查方法。造影室必须具备急救条件,一旦发生严重的过敏性休克，及时抢救，以确保患者的生命安全。对于一些特殊人群，减慢荧光素推注速度可能会降低不良反应的发生率。
Objective To investigate the adverse effects of fundus fluorescein angiography and preventive treatment measures.
Methods 3125 cases of patients with sodium fluorescein injection is invovled. The incidence of adverse reactions to their treatment were studied retrospectively.
Results In 3125 cases , a total of 234 cases of adverse reactions occurred, accounting for 7.48%.Most of which is mild to moderate adverse reactions, occurred in 219 cases, accounting for 7.01%, mainly nausea, vomiting, dizziness, skin rash; severe adverse reactions occurred in 15 cases, the incidence of 0.48%, mainly as syncope, allergiesshock; There is no death cases.Most adverse events present in the imaging start time within 1min.
Conclusion Although a number of adverse reactions occur, fundus fluorescein angiography technique is still a relatively safe method of fundus examination.Imaging rooms must have emergency conditions, in the event of severe anaphylactic shock, resuscitation, in order to ensure patient safety.For some special populations, slow speed of fluorescein injection may reduce the incidence of adverse reactions.