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| A NATURAL HISTORY OBSERVATION AND REGISTRY STUDY OF MACULAR TELANGIECTASIA TYPE 2: THE MACTEL STUDY |
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| 作者：Meidong … 文章来源：Save Sight Institute, Discipline of Clinical Ophthalmology and Eye Health, University of Sydney, Australia 点击数257 更新时间：2011/9/13 文章录入：毛进 责任编辑：毛进 |
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Macular telangiectasia is a group of uncommon, idiopathic, retinal vascular abnormalities affecting the retinal capillaries in which irregular capillary dilation and incompetence occur in the macula with or without vascular changes in the retinal periphery. There are three groups of the condition. The macular telangeictasia type 2 (MacTel Type 2) is the most common type.
Although MacTel Type 2 has been previously regarded as a rare disease, it is in fact probably much more common than previously thought. The very subtle nature of the early findings in MacTel type 2 means the diagnosis is often missed by optometrists and general ophthalmologists. No new information has emerged about the condition since its clinical features were first well described by Dr. J. Donald Gass in 1982. There is much work to be done to understand the disease better, to raise its profile and to search for treatments.
MacTel project was established in 2005 with a team of scientists and clinicians. The project is a comprehensive, international research collaboration of basic scientists, geneticists and clinicians (MacTel Research Group) to study MacTel Type 2. The project is sponsored by The Lowy Medical Research Institute.
The clinical study is conducted in up to 25 sites in the United States, Europe, Australia and Israel. The Save Sight Institute site led by Professor Mark Gillies is one of the leading site in the world for both clinical and laboratory research. This talk will address the newest aspects and findings of MacTel Type 2 researches that are conducted by MacTel Research Group.
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