| Purpose:To assess the improvements in clinical out comes based on implementing automated iris regis tration techno1ogy with Custom Vue wavefront-guided ablations．
MethOd：Two cohorts were treated to analyze improvements in clinical outcomes of wavefront—guided ablations using new iris registration techno1ogy．The first cohort of 26eyes was treated with automated iris registration and the pre-operative MRSE was-6．6D．The sccOnd cohort of 29 eyes was treated without automated iris registration
techno1ogy．Pre-operative MRSE of the second cohort was-6．36D．
Resuns：In the automated iris registration group，mean cyclorotation was measured at 2．07 degrees．At one week,77％ of patients achieved a UCVA of 20／20 and 96% achieved 20/25.
Meand MRSE at one week 79％ of patients achieved a UCVA or 20/20and 90% achieved 20／25．Mean MRSE at one week in second cohort was-0.08D．
Conclusion：Early results demonstrate slightly improved visual outcomes but most importantly increased safety with new automated iris registration technologyupgrades Automated iris registration optimizes clinical outcomes through alignment of wavefront map and laser ablation in all axises.
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