Objective. To evaluate the prevalence of age-related maculopathy (ARM) in adult Chinese living in rural or urban regions of mainland China.
Methods. The study included 4439 subjects (age 40+ years) out of 5324 subjects invited to participate (response rate 83.4%). It was held in rural and urban regions of Greater Beijing. The participants underwent a detailed ophthalmic examination including fundus photography. All fundus photographs were graded using the Wisconsin Age-Related Maculopathy Grading system.
Results. Fundus photographs were available for 4376 (98.6%) subjects. Early ARM was present in 122/8655 (1.4%; 95% confidence interval (CI): 1.16%, 1.66%) eyes or 63 / 4376 (1.4%; 95CI: 1.09%, 1.79%) subjects, late ARM in 12 / 8655 (0.14%; 95%CI:0.06%, 0.22%) eyes or 7/4376 (0.2%; 95CI:0.04%, 0.28%) subjects, and exudative ARM as part of late ARM in 7 / 8655 (0.1%; 95%CI:0.02%, 0.14%) eyes or 6/4376 (0.1%; 95CI:0.03%, 0.25%) subjects. The prevalence of early ARM, late ARM, and exudative ARM, respectively, increased from 0.61%, 0.07% and 0.07%, respectively, in the 40- to 44-year age group, to 1.66%, 0.26%, and 0.26%, respectively, in the 55- to 59-years old group, and to 2.99%, 0.90% and 0.60%, respectively, in the group aged 75 years and older. ARM was causative for visual impairment (best corrected visual acuity in the better eye: < 20/60 and ≥ 20/400) or blindness (visual acuity < 20/400) in 1 (0.023%) subject.
Conclusions. Visual impairment due to age-related maculopathy was relatively uncommon in the adult Chinese population in rural and urban regions.
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