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Triamcinolone Acetonide Induced Ocular Hypertension |
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作者:Jost B. … 文章来源:Department of Ophthalmology, Faculty of Clinical Medicine Mannheim,Ruprecht-Karls-University of Heidelberg, Germany 点击数:1750 更新时间:2006/7/9 17:20:51
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Purpose. To report on the clinical course of a patient showing markedly increased intraocular pressure (IOP) due to intravitreal triamcinolone acetonide.
Methods. A 33-year old patient received an intravitreal injection of approximately 20 mg triamcinolone acetonide as treatment of otherwise therapy resistant uveitis. She experienced an IOP rise to values over 40 mm Hg for a period for more than 3 months despite maximal antiglaucomatous medical therapy. Peak IOP was 55 mm Hg.
Results. Neither confocal scanning laser tomography nor qualitative assessment of optic disc photographs nor perimetry showed development of glaucomatous changes. Scanning laser polarimetry of the retinal nerve fibre layer suggested a slight loss in the nasal upper fundus quadrant.
Conclusions. Relatively young patients with a pronounced triamcinolone acetonide induced rise in intraocular pressure, unresponsive to maximal antiglaucomatous medication, may not necessarily undergo antiglaucomatous surgery if the rise in intraocular pressure does not last longer than approximately 3 months.
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