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Optical coherence tomography in macular degeneration of high myopia |
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| Optical coherence tomography in macular degeneration of high myopia |
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作者：Szu-Yuan… 文章来源：Department of Ophthalmology, Cathy General Hospital 280, Section 4, Ren-Ai Road, Taipei, Taiwan 点击数：4787 更新时间：2006/7/11 17:54:14 
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To evaluate the macular degeneration of high myopic eyes with optical coherence tomography
Methods
Review of medical records of macular degenerations in high myopia patients, staging as: T1(Tessellation 1), T2(Tessellation2), D1(Lacquer crack), D2(Diffuse atrophy), P1(Patch atrophy 1), P2(Patch atrophy 2), or MA (Macular atrophy), underwent high resolution OCT (Stratus OCT; Carl Zeiss Meditec Inc., Dublin, California, USA) scanning. The imaging was analyzed together with slit lamp biomicroscopy, visual acuity examination, refraction status and axial length. Ninety-eight eyes of forty-nine patients were included in the present study.
Results
In T1 cases, normal retinal architecture and normal thickness were found. Normal retinal architecture but decreased thickness was found in T2. In some T2 cases, retinal schisis with contracted posterior hyaloid membrane were found without foveal elevation. In D1 cases, dimpling at lacquer crack area and thinning of overlying neural retina were found. D2 cases showed neural retina thinning and minimal to moderate foveal schisis. Foveal detachments were found in some cases. In some P1 cases, partial retinal detachment was found. P2 cases showed thinning of neural retina without schisis or subretinal fluid in most cases. If sparing of neural retina was found as an island between P2 atrophic patches, the vision would be spared. Macular atrophic cases showed choroid and sclera thinning in addition to neural retina thinning. Large choroidal vasculature was found to be associated with overlying atrophy of neural retina and RPE layers.
Conclusion
High resolution OCT is a useful imaging technique in distinguishing and staging the macular degenerations associated with high myopia. It is also helpful in its tissue implication in pathogenesis of myopic maculopathy.
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