目的:观察地塞米松缓释剂(思诺迪清)前房植入对超声乳化白内障加人工晶状体植入术后后囊混浊的预防效果。方法:将2001.6~2002.1在我院手术的年龄相关性白内障随机分为A、B两组。A组(右眼,50)术中前房植入地塞米松缓释剂一粒。B组(左眼,46)作为对照组,术中前房未植入地塞米松缓释剂。随访2年,观察两组术后前房炎症及后发障的发生率。结果:术后前房炎症反应有显著性差异(P<0.05),后囊混浊的发生情况:轻度的有显著性差异(P<0.05),重度者无显著性差异(P>0.05)。结论:前房内植入地塞米松缓释剂可以减轻炎症,但不能有效地预防后发障的发生。
Clinical observation of anterior chamber implantation of dexamethasone sustained release microcapsules during phacoemulsification and intraocular lens operation ( Gao Chao // wenzhou medical college affiliated third hospital)
Abstract Objective: To evaluate the effect of dexamethasone sustained release microcapsules implanted in anterior chamber during phacoemulsification and intraocular lens implantation operation. Methods: Age-related cataract operation cases from 2001.6 to 2002.10 were divided into groups A (right eyes, 50 cases ) and B (left eyes, 46 cases ). Group A were implanted dexamethasone sustainted release microcapsules in the anterior chamber and group B without that during phacoemulsification and intraocular lens implantation operation. Results: There was Significance between two groups in anterior chamber inflammation and posterior capsule opacificationⅠ,but was not in posterior capsule opacification Ⅱ and more ( P>0.05 ). Conclusion: Dexamethasone sustained release microcapsules could release anterior inflammation, wherea could not prevent posterior capsule opacification effectively. |