| 目的：探讨影响近视眼角膜屈光力的相关因素。方法：分别测量227例（452眼）近视及近视散光患者角膜地形图、角膜中央厚度、眼压、A超及屈光度，将所得结果进行统计学分析。结果：①不同程度屈光度，角膜顶点屈光力低度近视组与中、高、重度近视组比较有显著性差异（P<0.05），角膜中央3mm屈光力，低、中度近视组与重度近视组比较有显著性差异（P<0.05），角膜中央5mm屈光力低度近视眼组与重度近视组比较有显著性差异（P<0.01），角膜中央7mm屈光力各组之间比较无显著性差异（P>0.05）。
②角膜中央3mm、5mm、7mm的屈光力与年龄、前房深度呈正相关（年龄：r分别为：0.398, 0.387, 0.342, P=0.000；前房深度：r分别为：0.277, 0.310, 0.288, P=0.000）。
③角膜中央3mm、5mm、7mm的屈光力均与等效球镜屈光度、眼轴、晶体厚度呈负相关（等效球镜屈光度：r分别为―0.80, ―0.782, ―0.710, P=0.000; 眼轴：r分别为：―0.670, ―0.668, ―0.598, P=0.000；晶体厚度r分别为―0.318, ―0.282, ―0.232, P值分别为0.000, 0.000, 0.001）。
④将角膜不同区域屈光力为应变量，分别建立多元线性回归方程：Y3=77.571―1.432X1―0.554X2+0.964X3+0.067X4―1.205 X5; (F= 101.356, P=0.000)
作者单位（410008） 中国长沙市中南大学湘雅医院眼科激光中心
Y5=76.538―1.424X1―0.538X2+1.063X3+0.067X4―1.122X5; (F= 92.395, P=0.000)
Y7=72.563―1.308X1―0.462X2+1.078X3+0.062X4―0.926X5; (F= 67.398, P=0.000)
（其中Y3、Y5、Y7）分别为角膜中央3mm、5mm、7mm的屈光力，X1、X2、X3、X4、X5分别为眼轴长度、等效球镜度数、前房深度、年龄及晶体厚度。
结论：影响近视眼角膜屈光力的主要因素是眼轴、眼球屈光度、前房深度、年龄及晶体厚度。
[关键词]：近视；角膜；屈光力
Mutiple Factors analysis of conenl refractive power in myopia
Wu Xiaoying, Liu Shuang-zhen, Hu Sheng-fa, et al.
Ophthalmic laser center, XiangYa Hospital, central South University, Changsha 410008, China.
[Abstract] Aim to investigate the factors correlated to coneal refractive power in patients with myopia. Methods: Corneal topography, Central coneal thickness(CCT), intraocular pressure (IOP), A scan ultrasonogra- phy and retinophotoscopy were performed on eyes of cases of mypopia or myopia astigmatism, and the relationships amony the parameter were anal -yzed statically. Results: ①There were the statistical differences between mild myopia group and moderate, hight of 3mm zone, there were the statistical difference between mild, moderate myopia group and heavy myopia group(P<0.05). In the diopter of 5 mm zone, there were the statistical difference between mild myopia group and heavy myopia group (P<0.01). ②A positive correlation was build up between the diopter of 3mm, 5mm, 7mm zone and age(r=0.398, 0.387, 0.342, P<0.001), anterior chamber depth(r=0.277, 0.31, 0.288, P<0.001), and a negative correlation to ocular dipter(r=－0.780, －0.782, －0.71, P<0.001), the length of ocular axis (r=－0.670, －0.668, －0.598, P<0.001) thickness of lens (r=－0.318, －0.282, －0.232, P<0.001). ③The regression equation for the diopter of 3mm(Y3), 5mm(Y5), 7mm(Y7) zone was figured out as Y3=77.571－1.432X1－0.054X2+0.964X3+ 0.067X4 －1.205X5 (F=101.356, P=0.000);
Y5=76.538―1.424X1―0.538X2+1.063X3+0.067X4―1.122X5(F= 92.395, P=0.000);Y7=72.563―1.308X1―0.462X2+1.078X3+0.062X4―0.926X5 (F= 67.398, P=0.000). X1=length of ocular axis(mm), X2=Ocular diopter (D), X3=anterior chamber depth(mm), X4=age(year), X5=thickness of lens(mm). Conclusion: The main influence factors of cornear refractive power were the length of ocular axis, Ocular diopter, anterior chamber depth, age and thickness of lens.
[Key words] Myopia; Cornea; Refractive power |
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