The authors report a rare case with bilateral conjunctival nodules in Sweet’s syndrome(SS). The patient was a 47-year-old Chinese male, who fulfilled the diagnostic criteria of SS. Fever as well as erythematous papules and blains on his face and arms resolved completely after administration of oral prednisolone. However, he developed secondary facial milia and painless nodules in bilateral eyes. Two well demarcated conjunctival nodules with hyperemia were found, one in the temporal aspect of the right eye and the other in the nasal aspect of the left eye. Excision biopsy of the right eye’s lesion showed neutrophilic infiltration without vasculitis, the same histopathologic feature of SS. The one in the left eye was responsive to local corticosteroids. To date, this is the first reported case of bilateral conjunctival nodules in SS home and abroad. It is also the first report with ocular surface abnormality in SS in China.
We present figures of high quality in the attachment, including the histopathologic results of the primary erythematous papules, the secondary white milia and the conjunctival nodule, as well as the figures of the facial lesions at initial and final visit and the conjunctival nodules pre and post operatively to show the treatment effect.