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Full Correction and Undercorrection of Myopia Evaluation Trial (FUMET): Design, Baseline and 6 month Data |
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| Full Correction and Undercorrection of Myopia Evaluation Trial (FUMET): Design, Baseline and 6 month Data |
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作者：李仕明 文章来源：首都医科大学附属北京同仁医院眼科中心 点击数：214 更新时间：2012/9/13 
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Purpose The full correction and undercorrection of myopia evaluation trial (FUMET) is a 2-year, randomized, double-blinded, controlled trial to determine whether there is a difference in the rate of myopia progression between Chinese children wearing single vision lenses with undercorrection by 0.5 D versus full correction of their myopia.
Methods Chinese children aged 7~15 years were recruited from one optometric center in Anyang city in Central China between October 2010 and March 2011. After blocking by gender, children with low to moderate myopia (cycloplegic spherical error from -1.5 D to -6.0 D), astigmatism less than -1.5 D and anisometropia less than 1.0 D were randomly allocated to wear single vision lenses with full correction or undercorrection by +0.5 D during the next 2 years. Progression of myopia in the right eye measured by cycloplegic autorefraction and axial length by IOL Master are the primary outcome measures. Ocular examinations and questionnaire survey for myopia-related factors will be performed every 6 months.
Results. We enrolled 200 Chinese children with mean age of 11.1±2.0 years (range 7~15 years) and 100 were girls. At baseline, the mean cycloplegic spherical equivalent and the axial length between the two groups were -2.95±1.03 D and -2.92±0.93 D (P=0.89), 24.51±0.75 mm and 24.54±0.78 mm (P=0.78), respectively. At 6 month, 160 children were followed with mean myopia progression of -0.45±0.39 D and -0.44±0.44 D (P=0.99), and mean axial length elongation of 0.17±0.13 mm and 0.18±0.13 mm in full correction group and undercorrection group, respectively (P=0.70).
Conclusion The findings at 6 month indicated that undercorrection of myopia by 0.5 D didn’t accelerate the progression of myopia in Chinese children who spent relatively more time in near work than children in other countries. However, it deserves further observation during the follow up. |
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