Aims To investigate the change of macular thickness after uncomplicated cataract phacoemulsification surgery with intracameral cefuroxime.
Methods Prospective, controlled and parallel compared clinical study. Enrolled patients were divided into 4 groups based on age under or over 60 years old (<60 group and ≥60 group) and with intracameral cefuroxime (experiment group) before ending operation or with irrigating solution (control group). Macular thicknesses were measured at baseline and 1 month and 6 months postoperatively.
Results At 1 month, ≥ 60 experiment group has thicker fovea, inferior inner area and temporal inner area than other 3 groups. At 6 months, only inferior inner area was thicker in ≥ 60 experiment groups than other 3 groups. With response to preoperative value, at 1 month, 4 sectors of macular thickness were thicker in ≥60 experiment group than other 3 groups, which were forvea, inferior inner area, temporal inner area and inferior outer area. At 6 months, only 2 areas were thicker in ≥60 experiment group than other 3 groups, which were fovea and inferior inner area.
Conclusions 1) Macula become thicker after cataract surgery which cannot restore preoperative level at 6 months, 2) Patients elder than 60 will have thicker macula after cataract surgery with intracameral cefuroxime at 1 month postoperatively. |
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