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| Effectiveness of selective laser trabeculoplasty (SLT) in POAG patients with insufficient control of intraocular pressure despite maximum tolerated medical therapy. |
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作者：律鹏 文章来源：兰州大学第二医院眼科 点击数：995 更新时间：2012/9/13 
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Objective To evaluate the IOP lowering effect of selective laser trabeculoplasty (SLT) in patientswith primary open-angle glaucoma (POAG)on maximum tolerated medical therapy (MTMT) on IOP reduction.
Methods A total of 39 patients (39 eyes) with a diagnosis of primary open angleglaucomawith uncontrolled IOP despite MTMT underwentSLTtreatment circumferentially over 360°. Follow-up visits were conducted 1 day afterSLTand then 1, 3 and 6months post-treatment. The initial medication was continued unchanged for 6 months.
Results Thirty-nine patients were treated. Data collection terminated with 37patients reaching 6-months follow-up. Average energy was 51.14 mJ (0.52mJ x 89 spots). Preoperative mean intraocular pressure (IOP) was 27.9 ± 3.5mmHg, Six months postoperatively the mean IOP decreased to 22.8 ± 2.6 mmHg (The success rate was 42.5%;P<0.001).Complications included conjunctival redness within 1 day postoperatively in 12 eyes (32.4%). One hour after SLT treatment, an increase in IOP greater than 5 mm Hg was detected in 2 eyes (5.4%) and resolved within 24 hours with topical medication. Six patients (six eyes) needed additional surgery to lower IOP.
Conclusion Even in patients on maximum IOP lowering medication, SLT has the potential to significantly reduce IOP after treatment which can be considered as an option for in POAG patients with insufficient control of intraocular pressure despite maximum tolerated medical therapy. |
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| 会议投稿录入：毛进 责任编辑：毛进 |
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