| Study on tear film lipid layer of normal adults with a tear scope
LI Hai-Yan, PANG Guo-Xiang, Jin Yu-Mei
【Abstract】 Objective To observe tear film lipid layer interference patterns in normal volunteers with a tear scope and to assess the value of lipid layer examination in the diagnosis of dry eye. Methods A series of 332 volunteers was examined with a tear scope to evaluate the tear film lipid layer;120 of them was also examined with a measurement of tear breakup time (TBUT) and SchirmerI test (SIt). Results Grades of lipid layer interference patterns had a good correlation with ages but a poor correlation with gender.The difference of TBUT among each grade of lipid layer showed statistical significance (p<0.01),while the difference of SIt showed no statistical significance (p>0.05). The current diagnostic standard taken as gold standard, the lipid layer examination had a sensitivity of 38.9% and a specificity of 72.8% in the diagnosis of dry eye. Conclusion An examination of tear film lipid layer with a tear scope tends to be useful in the diagnosis of dry eye.
目的 探讨泪膜镜脂质层形态检查的临床意义以及不同年龄组泪膜脂质层形态的特点。方法 健康成年人332例，应用Keeler泪膜镜进行泪膜脂质层形态观察，并对其中120例行泪膜破裂时间测定和SchirmerI 试验检查。 结果 脂质层分级与年龄有相关关系，与性别无相关关系。不同脂质层分级的TBUT结果之间差异有非常显著性意义（p<0.01）。不同脂质层分级的SIt结果之间差异无显著性意义（p>0.05）。以目前诊断标准，泪膜脂质层检查在干眼症诊断中的灵敏度为38.9％，特异度为72.5％。 结论 应用泪膜镜进行泪膜脂质层形态检查是一种诊断干眼症的较好的检查手段。
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