Purpose To analyze in-vitro attachment of lens epidermal cells to poly(ethylene glycol) methyl ether methacrylate（PEGMEM）modified silicone intraocular lens materials.
Methods The test materials were modified by using argon plasma treatment to bind PEGMEM to the surface. The control materials were not modified. Chemical changes on the surface were analyzed by Fourier transform infrared attenuated total reflection (FTIR-ATR) to confirm the covalent binding of PEGMEM. IOL materials hydrophilicity was determined by measuring water contact angle. Lens epidermal cells (LECs) were seeded onto the surface and incubated for 8h. LECs attachment was observed by confocal fluorescence microscopy.
Results FTIR-ATR analysis confirmed that the test IOL materials were surface modified with PEGMEM. The hydrophilicity of the IOL materials was greatly improved by surface modification.
Conclusions PEGMEM-modified hydrophilic IOLs materials showed a reduced LECs adherence and could be helpful in preventing the occurrence of posterior capsule opacification. | 
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