Purpose: To evaluate factors that predict the visual prognosis following
cataract surgery in patients with Behcet's disease (BD). Setting: The First
Affiliated Hospital ofChongqingMedicalUniversity,Chongqing,China Design: Retrospective clinical study Methods: Thirty-six eyes of 27 BD patients with complicated
cataract underwent phacoemulsification (Phaco) cataract surgery and intraocular
lens (IOL) implantation between September 2008 and March 2011. The data
including best corrected visual acuity (BCVA), full-field electroretinogram
(ERG), intraocular inflammation, extraocular manifestations and complications
before and after surgical intervention were analyzed. Results: Twenty-one male (26 eyes)
and 6 female (10 eyes) BD patients with complicated cataract were included. There
were no complications after surgery although a mild to moderate anterior
chamber reaction was present in all patients. At last visit BCVA was improved in
35 eyes. Twenty-seven eyes (75%) achieved a final BCVA of 0.1 or better. All
female patients did not have obvious fundus complications and achieved a final BCVA
of 0.25 or better. The common causes for poor visual prognosis were optic
atrophy, atrophy of the retina and cystoid macular edema. Eyes with marked ERG a-
and b-wave abnormalities showed a significantly worse postoperative BCVA. Seven
(10 eyes) out of 8 patients (11 eyes) with a history of erythema nodosum (EN)
had a postoperative visual acuity below 0.1. Conclusions: Phaco and IOL implantation
in BD patients can be safely and successfully performed in quiet eyes. A poor
visual prognosis is associated with male gender, severe fundus complications
and EN and can be predicted by ERG abnormalities. |