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RGP镜矫正屈光参差性弱视的视觉诱发电位评估         
RGP镜矫正屈光参差性弱视的视觉诱发电位评估
作者:陈俊,乔… 文章来源:四川省绵阳市中心医院眼科 点击数:1988 更新时间:2006/3/22 18:14:32
目的:分析高透氧硬性角膜接触镜(Rigid gas permeable contact lens,RGP) 联合常规弱视治疗干预屈光参差性弱视眼前后的视觉诱发电位(VEP)变化规律,探讨RPG增强常规弱视治疗对屈光参差性弱视疗效的相关机理。方法:将2003年1月~2004年12月在我科门诊诊断为屈光参差性弱视患者43例,,随机分为A、B两组,A组22人,B组21人,A组配戴高透氧硬性角膜接触镜,B组配戴框架眼镜,戴镜后两组同时进行正规弱视综合治疗,对比观察两组治疗3个月、6个月后视力、立体视、VEP等的变化。结果:3个月后,两组裸眼和矫正视力均有不同程度提高,A组有效率达77.3%,平均提高2.01行,B组有效率达14.3.00%, VEP异常发生率B组多于A组;两组疗效具显著性差异。 6个月后,A组有裸眼和矫正视力均有不同程度提高,有效率达90.91%,平均提高2.35行,B组例矫正视力提高,有效率达19.04%,VEP异常发生率B组明显多于A组,两组疗效具显著性差异。结论:RGP矫正屈光参差性弱视安全、有效,可以通过VEP等电生理手段客观评价其在弱视矫正中的作用,并为屈光参差性弱视的病理机制提供证据。 Objective: To evaluate the effect of using Rigid Gas Permeable Lens(RGP) to cure anisometopic amblyopia by VEP ,visual acuity. Methods: 43 patients with anisometropic amblyopia were divided into two groups, group A (22patients) with RGP and B group (21 patients) with rimway mounting were given amblyopia therapy as covering and so on. And observe the effect comparatively. Result: After3 months, in A group there were 17 patients with both the bole vision and the corrected vision increasing (with effective rate 77.3%) while in B group there were only 3 patient whose corrected vision was enhanced (with effective rate 14.3%). The results differed significantly between the two groups (χ2=32.84 P<0.01). After6 months, in A group there were 20 patients with both the bole vision and the corrected vision increasing (with effective rate 90.91%) while in B group there were only 4patient whose corrected vision was enhanced (with effective rate 19.02%). The results differed significantly between the two groups (χ2=47.25, P<0.01). Both after 3mon and after 6mon, ratio of anomal-VEP in group A is more than group B. Conclusion:Using RGP is a safe and effective way to cure anisometropic amblyopia, VEP can be helpful to evaluate effect of amblyopia therapy.
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